Safe oxygen saturation targeting and monitoring in preterm infants: can we avoid hypoxia and hyperoxia?
نویسندگان
چکیده
UNLABELLED Oxygen is a neonatal health hazard that should be avoided in clinical practice. In this review, an international team of neonatologists and nurses assessed oxygen saturation (SpO2 ) targeting in preterm infants and evaluated the potential weaknesses of randomised clinical trials. CONCLUSION SpO2 of 85-89% can increase mortality and 91-95% can cause hyperoxia and ill effects. Neither of these ranges can be recommended, and wider intermediate targets, such as 87-94% or 88-94%, may be safer.
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In recent years, oxygen targeting has become a relevant topic in neonatal intensive care medicine.1 Despite large SpO2 targeting trials including numerous subjects and the available results of a meta-analysis of these data,2,3 there is still an ongoing debate on the optimum SpO2 target range in preterm infants. Both conditions, hyperoxia as well as hypoxia, frequently occur in extremely low bir...
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